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Valentina Greco, PhD
Carolyn Slayman Professor of Genetics
Yale University School of Medicine
Yale Stem Cell Center
Yale Cancer Center
333 Cedar Street, SHM I 336B
New Haven, CT 06520



Press Coverage about our Publications


Marsh E, Gonzalez DG, Lathrop EA, Boucher J and Greco V✉. Positional stability and membrane occupancy define skin fibroblast homeostasis in vivo. Cell. 2018 Nov 8;175(6):1620-1633.

Revitalizing Aging Skin through Diet

Mesa K*, Kawaguchi K*, Cockburn K*✉, Gonzalez DG, Boucher J, Xin T, Klein AM✉ and Greco V✉. Homeostatic stem cell self-renewal is driven by local differentiation. Cell Stem Cell. 2018 Nov 1;.23:1-10.

Neighbors hold key to the renewal of stem cells

Brown S*, Pineda CM*, Xin T, Boucher J, Suozzi KC, Park S, Matte-Martone C, Gonzalez DG, Rytlewski J, Beronja S, Greco V. Correction of aberrant growth preserves tissue homeostasis. Nature. 2017 Aug 17;548:334-337.

Policing Tumorigenesis within the Skin: Good Outs Bad

Cell biology: Healthy skin rejects cancer

Good cellular neighbors combat incipient cancers


Rompolas P*, Mesa KR*, Kawaguchi K, Park S, Gonzalez D, Brown D, Boucher J, Klein AM & Greco V. Spatiotemporal coordination of stem cell commitment during epidermal homeostasis. Science. 2016 Jun 17;352(6292):1471-4

Fate by Chance, not by Choice: Epidermal Stem Cells Go Live

Research note: Images show how stem cells create just enough tissue

Mesa KR, Rompolas P, Zito G, Myung P, Sun TY, Brown S, Gonzalez D, Blagoev K, Haberman A and Greco V.  Niche induced cell death and epithelial phagocytosis regulate hair follicle stem cell pool. Nature. 2015 Jun 4;522(7554):94-7

Research in the News: Tiny hair follicle offers big clues about the life and death of stem cells

Follicle Stem Cells Done in by Neighbors

Deschene RE*, Myung P*, Rompolas P, Zito G, Sun TY, Taketo MM, Saotome I and Greco V. β-catenin activation regulates tissue growth via a non-cell autonomous mechanism within the hair stem cell niche. Science. 2014 Mar 21;343(6177):1353-6

A key link between tumors and healthy tissue identified

Rompolas P, Mesa KR and Greco V. Spatial organization within a niche as a determinant of stem cell fate. Nature. 2013 Oct 24;522(7472):513-8

In stem cells, like real estate, location is most important factor

Rompolas P, Deschene ER, Zito G, Gonzalez DG, Saotome I, Haberman AM and Greco V. Live imaging of stem cell and progeny behavior in physiological hair follicle regeneration. Nature. 2012 Jul 26;487(7408):496-9

Reporting Live from the Epidermal Stem Cell Compartment!

In real time, Yale scientists watch stem cells at work regenerating tissue


Press Coverage about our Lab Members

“Women in Stem Cell Science: Part I” - Stem Cell Reports. 2018 Sept 11;3(11):609-612

"Inner Workings: Microscopy lights up stem cells in action" - An Interview with Valentina Greco

"How Cell Biologists Work: Valentina Greco on cultivating a passionate research team" - An Interview with Valentina Greco

“Being part of a group enhances joy and reduces the negative effects of failure” - An Interview with Valentina Greco

Pantelis Rompolas

2014 Blavatnik Awards